Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Nitrosalicylic acid → 2-Hydroxy-4-nitrobenzyl alcohol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Nitrosalicylic acid | HCID 69266 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 2-Hydroxy-4-nitrobenzyl alcohol | HCID 11816094 | — |
반응 단계
10.0 g (54.6 mmol) of 4-nitrosalicylic acid are initially charged in 100 ml of THF. With ice-cooling, 109 ml of 1 M borane/THF complex are added, and the mixture is stirred at RT overnight. The mixture is concentrated and the precipitate is filtered off with suction. The solid is dissolved in ethyl acetate and dried over magnesium sulfate. After concentration and drying under high vacuum, the title compound is directly reacted further.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08884017B2 |
| 출처 데이터셋 | uspto-grants-2014_11 |
| ORD ID | ord-233a740a673244c8a19524f936c63ad0 |
| 출처 메모 | uspto-grants-2014_11 |