Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Propylenediamine → 5,6-Bis(4-fluorophenyl)-2-methyl-2,3-dihydropyrazine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Propylenediamine | HCID 6567 | — |
| 반응물 | 4,4'-Difluorobenzil | HCID 123072 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 5,6-Bis(4-fluorophenyl)-2-methyl-2,3-dihydropyrazine | HCID 57543618 | 86% |
반응 단계
First, with ethanol as a solvent, 5.31 g of 4,4′-difluorobenzil (by Tokyo Chemical Industry Co., Ltd.) and 1.60 g of 1,2-diaminopropane (by Tokyo Chemical Industry Co., Ltd.) were mixed, and the mixture was refluxed for three hours. After reaction, a reaction solution was condensed by using an evaporator, and an obtained residue was recrystallized by using ethanol; thus, 2,3-bis(4-fluorophenyl)-5-methyl-5,6-dihydropyrazine was obtained (light yellow powder, yield: 86%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08889266B2 |
| 출처 데이터셋 | uspto-grants-2014_11 |
| ORD ID | ord-3e3f3068b37a445a93ca72c14d52bfcf |
| 출처 메모 | uspto-grants-2014_11 |