참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Ethyl 6-chloro-4-hydroxy-3-quinolinecarboxylate | HCID 718113 | — |
| 반응물 | HCID 178479711 | HCID 178479711 | — |
| 생성물 | Ethyl 4,6-dichloroquinoline-3-carboxylate | HCID 1479087 | — |
반응 단계
Ethyl-6-chloro-4-oxo-1,4-dihydroquinoline-3-carboxylate (19.8 mmol) and phosphorus (V) oxychloride (99.3 mmol) was stirred and heated to 125° C. for 12 hours. The mixture was cooled to ambient temperature and the phosphorus (V) oxychloride was evaporated. The crude product was used without further purification. MS m/z 271.80 (M+1).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US08889706B2 |
|---|
| 출처 데이터셋 | uspto-grants-2014_11 |
|---|
| ORD ID | ord-7f5f899c7f9c44a4b10cfe57c6ae087e |
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| 출처 메모 | uspto-grants-2014_11 |
|---|
