참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Formamide | HCID 713 | — |
| 반응물 | p-Toluenesulfinic acid | HCID 10818 | — |
| 반응물 | Benzaldehyde, 4-(phenylmethoxy)- | HCID 78109 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | N-((4-(Benzyloxy)phenyl)(tosyl)methyl)formamide | HCID 59797510 | 49% |
반응 단계
A mixture of 4-methylbenzenesulfinic acid (3.1 g, 19.9 mmol), 4-(benzyloxy)benzaldehyde (4.2 g, 19.9 mmol), and formamide (4.5 mL ) was heated at 60° C. for 20 h. The mixture was diluted with methanol and stirring was continued for 1 h at rt. The resultant solid was filtered and dried to give 3.81 g (49%) of a white solid. The product was used in the next step without future purification.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US07429665B2 |
|---|
| 출처 데이터셋 | uspto-grants-2008_09 |
|---|
| ORD ID | ord-89e71a12bdda428480b51ec0550a9332 |
|---|
| 출처 메모 | uspto-grants-2008_09 |
|---|
