Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3,4-dihydro-2H-pyran → 2-[(3-Bromophenyl)methoxy]oxane
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3,4-dihydro-2H-pyran | HCID 8080 | — |
| 반응물 | Triphenylphosphonium bromide | HCID 80811 | — |
| 반응물 | 3-Bromobenzyl alcohol | HCID 85141 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 2-[(3-Bromophenyl)methoxy]oxane | HCID 15282064 | — |
반응 단계
The alcohol of Step 1 (41.23 mmol), dihydropyran (12.5 mL, 137 mmol) and triphenylphosphine hydrobromide (725 mg, 2.11 mmol) were mixed together in 200 mL of CH2Cl2 and stirred for 2 days. The solvent was then evaporated and the title product was purified by flash chromatography on silica using EtOAc:toluene.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05856322 |
| 출처 데이터셋 | uspto-grants-1999_01 |
| ORD ID | ord-26550fcdd4ce4475a6345906644a73e3 |
| 출처 메모 | uspto-grants-1999_01 |