Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Cyclohexylacetaldehyde → 6-methyl-1-(cyclohexylmethyl)-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Cyclohexylacetaldehyde | HCID 316627 | — |
| 반응물 | 5-Methyltryptamine hydrochloride | HCID 6917145 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 6-methyl-1-(cyclohexylmethyl)-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole hydrochloride | HCID 18702265 | — |
반응 단계
A suspension of cyclohexylacetaldehyde (631 mg 5.0 mmol.) and 5-methyltryptamine hydrochloride (1.0 g, 4.3 mmol.) in ethanol. (20 mL) was heated to reflux for 36 hours under nitrogen atmosphere. The reaction mixture was cooled to ambient temperature and the crude product isolated by filtration. The solid was triturated with ethanol and washed with diethyl ether. The product was isolated by filtration (731 mg). m/e=282, mp 230° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05861425 |
| 출처 데이터셋 | uspto-grants-1999_01 |
| ORD ID | ord-14035a2428ae4cf68ed227cef150498e |
| 출처 메모 | uspto-grants-1999_01 |