Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Diethyl Ether → N,N-Bis(2-chloroethyl)benzylamine hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Diethyl Ether | HCID 3283 | — |
| 반응물 | Chloroform | HCID 6212 | — |
| 반응물 | 2,2'-((Phenylmethyl)imino)bisethanol | HCID 7553 | — |
| 반응물 | Thionyl Chloride | HCID 24386 | — |
| 생성물 | N,N-Bis(2-chloroethyl)benzylamine hydrochloride | HCID 2777881 | — |
반응 단계
Combine thionyl chloride (25.4 g, 130 mmol) and chloroform (20 mL). Add over about 1 hour, a solution of N,N-bis(2-hydroxyethyl)benzylamine (25.4 g, 130 mmol) in chloroform (20 mL). After the addition is complete, heat to reflux. After 1 hour, cool the reaction mixture to ambient temperature and add diethyl ether to form a solid. Collect the solid by filtration, rinse with diethyl ether, and dry to give N,N-bis(2-chloroethyl)benzylamine hydrochloric acid salt.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05861417 |
| 출처 데이터셋 | uspto-grants-1999_01 |
| ORD ID | ord-81dc470047bc4c2ca0422c8d8bc03f42 |
| 출처 메모 | uspto-grants-1999_01 |