Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Triethylamine → 3-(2,5-Dimethylphenyl)-1-ethyl-2-thioxo-imidazolidin-4-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | 2,5-Dimethylphenyl isothiocyanate | HCID 140499 | — |
| 반응물 | N-Ethylglycine | HCID 316542 | — |
| 용매 | Chloroform | HCID 6212 | — |
| 생성물 | 3-(2,5-Dimethylphenyl)-1-ethyl-2-thioxo-imidazolidin-4-one | HCID 11817510 | 42.7% |
반응 단계
The title compound was prepared by the procedure described in Example 9 using 16.3 g of 2,5-dimethylphenyl-isothiocyanate, 18.4 g of N-ethyl glycine, 20.2 g of triethyl amine, and 250 mL of chloroform. Crystallization from ethyl acetate afforded the title compound (10.6 g) as an off-white solid, m.p. 176°-178° C. Anal. Calcd. for. C13H16N2OS: C, 62.87; H, 6.49; N, 11.28. Found: C, 62.70; H, 6.46; N, 11.27. Mass spectrum (EI, M.+) m/z 248.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05861517 |
| 출처 데이터셋 | uspto-grants-1999_01 |
| ORD ID | ord-fbbdbce8eb584f1faae36ae160e84bd0 |
| 출처 메모 | uspto-grants-1999_01 |