Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
tert-Butyl isocyanate → 1-[2-Amino-6-(2,3-dichlorophenyl)pyrido[2,3-d]pyrimidin-7-yl]-3-tert-butylurea
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | tert-Butyl isocyanate | HCID 62412 | — |
| 반응물 | 6-(2,3-Dichlorophenyl)-pyrido[2,3-d]pyrimidine-2,7-diamine | HCID 21850048 | — |
| 생성물 | 1-[2-Amino-6-(2,3-dichlorophenyl)pyrido[2,3-d]pyrimidin-7-yl]-3-tert-butylurea | HCID 5329112 | — |
반응 단계
Following the general procedure of Example 2, 0.502 g of 6-(2,3-dichlorophenyl)-pyrido[2,3-d]pyrimidine-2,7-diamine from Example 83 was reacted with 0.206 mL of tert-butyl isocyanate. The product is purified by silica gel chromatography eluting with a gradient of CHCl3 :EtOAc (98:2) to CHCl3 :EtOAc (1:2) to afford the title compound; mp 356°-358° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05733913 |
| 출처 데이터셋 | uspto-grants-1998_03 |
| ORD ID | ord-9b59e62182af43278d1cf7bf128220cd |
| 출처 메모 | uspto-grants-1998_03 |