Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Diethyl Malonate → diethyl (S)-2-methylbutylmalonate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Diethyl Malonate | HCID 7761 | — |
| 반응물 | Sodium | HCID 5360545 | — |
| 반응물 | 1-Bromo-2-methylbutane, (+)- | HCID 5464167 | — |
| 반응물 | Sodium Methoxide | HCID 10942334 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | diethyl (S)-2-methylbutylmalonate | HCID 12600622 | — |
반응 단계
Sodium (57.5 g, 2.5 mols) was added to ethanol (1 l) to prepare sodium methoxide, followed by adding (S)-2-methylbutyl bromide (317 g, 2.1 mols) and diethyl malonate 400 g, 2.5 mols), refluxing the mixture for 5 hours and distilling off ethanol to obtain oily diethyl (S)-2-methylbutylmalonate.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05059340 |
| 출처 데이터셋 | uspto-grants-1991_10 |
| ORD ID | ord-98696a3edf844093a91efe5755259a25 |
| 출처 메모 | uspto-grants-1991_10 |