참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Urea | HCID 1176 | — |
| 반응물 | 5H-Dibenz(c,e)azepine, 6,7-dihydro- | HCID 81183 | — |
| 생성물 | 5,7-dihydro-6H-dibenz[c,e]azepine-6-carboxamide | HCID 20041714 | — |
반응 단계
A mixture of 1.95 g of 6,7-dihydro-5H-dibenz[c,e]azepine and 3 g of urea is stirred at 120° C. for 15 minutes and then poured onto ice/water. After extracting the resulting aqueous mixture with methylene chloride the combined extracts are washed with water, dried over anhydrous sodium sulphate and evaporated. The solid residue is recrystallized from n-hexane/ethyl acetate, and in this manner there is obtained pure 5,7-dihydro-6H-dibenz[c,e]azepine-6-carboxamide, m.p. 212°-214° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04766115 |
|---|
| 출처 데이터셋 | uspto-grants-1988_08 |
|---|
| ORD ID | ord-57670e097dfc4a52a1ddf6e89ecb4ec1 |
|---|
| 출처 메모 | uspto-grants-1988_08 |
|---|
