Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
cis-1-Acetyl-6-(4-benzyl-3,5-dimethylpiperazin-1-yl)-5-methoxyindoline → cis-6-(3,5-Dimethylpiperazin-1-yl)-5-methoxyindoline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | cis-1-Acetyl-6-(4-benzyl-3,5-dimethylpiperazin-1-yl)-5-methoxyindoline | HCID 69835917 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Hydrochloric Acid | HCID 313 | — |
| 생성물 | cis-6-(3,5-Dimethylpiperazin-1-yl)-5-methoxyindoline | HCID 11265480 | — |
반응 단계
The title compound was prepared from D4 by hydrogenation over 10% Pd/C using a similar procedure to Example 45 (98%), followed by hydrolysis in 2M HCl using a similar procedure to Description 3 (80%) to afford the product as a pale brown solid
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06747030B1 |
| 출처 데이터셋 | uspto-grants-2004_06 |
| ORD ID | ord-7364dfedd8244a10939e58d2c4a3bb0e |
| 출처 메모 | uspto-grants-2004_06 |