Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Acetamidobenzaldehyde → 2-Ethylhexyl 3-(4-acetylaminophenyl)-2-cyanoacrylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Acetamidobenzaldehyde | HCID 73942 | — |
| 반응물 | 2-Ethylhexyl cyanoacetate | HCID 96359 | — |
| 용매 | Isopropanol | HCID 3776 | — |
| 생성물 | 2-Ethylhexyl 3-(4-acetylaminophenyl)-2-cyanoacrylate | HCID 69201897 | 54% |
반응 단계
A mixture of 35 g (0.18 mol) of 2-ethylhexyl cyanoacetate and 30 g (0.18 mol) of 4-acetamidobenzaldehyde in 300 ml of isopropanol is refluxed for 3 hours. The reaction mixture is then allowed to cool and is crystallized. The crystals formed are separated out by filtration and are recrystallized from a minimum amount of isopropanol. After filtration and drying, 33.3 g (54% yield) of 2-ethylhexyl 3-(4-acetylaminophenyl)-2-cyanoacrylate are obtained in the form of a pale yellow powder.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06749839B2 |
| 출처 데이터셋 | uspto-grants-2004_06 |
| ORD ID | ord-6cb71ca2a1374163a3fe5991ff5e5074 |
| 출처 메모 | uspto-grants-2004_06 |