Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N,N-Bis(2-chloroethyl)benzylamine hydrochloride → Ethyl 1-benzyl-4-{[3-(2-butynyloxy)phenyl]sulfonyl}-4-piperdine carboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N,N-Bis(2-chloroethyl)benzylamine hydrochloride | HCID 2777881 | — |
| 반응물 | Ethyl{[3-(2-butynyloxy)phenyl]sulfonyl}acetate | HCID 23513876 | — |
| 생성물 | Ethyl 1-benzyl-4-{[3-(2-butynyloxy)phenyl]sulfonyl}-4-piperdine carboxylate | HCID 17944926 | 63% |
반응 단계
Ethyl 1-benzyl-4-{[3-(2-butynyloxy)phenyl]sulfonyl}4-piperdine carboxylate was prepared according to the general method as outlined in example 1 (step 6), starting from ethyl{[3-(2-butynyloxy)phenyl]sulfonyl}acetate (3 g, 10.1 mmol) and Benzyl-bis-(2-chloro-ethyl) amine hydrochloride (2.88 g, 10.7 mmol); 2.91 g yellow oil. Yield 63%; MS: 456.3 (M+H)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06753337B2 |
| 출처 데이터셋 | uspto-grants-2004_06 |
| ORD ID | ord-36df0c6318ad42adbe9162d5edc677d2 |
| 출처 메모 | uspto-grants-2004_06 |