Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 354891생성일: 2026년 10월 24일
Dimethyl[[6-(3-cyclopentylpropionamido)-4-quinazolinylamino]methylene]propanedioate → methyl 4-oxo-10-(3-cyclopentylpropionamido)-4H-pyrimido[1,2-C]quinazoline-3-carboxylate
https://huagongshe.com/ko/reaction/354891
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Dimethyl[[6-(3-cyclopentylpropionamido)-4-quinazolinylamino]methylene]propanedioate | HCID 13060507 | — |
| 용매 | Diphenyl Ether | HCID 7583 | — |
| 생성물 | methyl 4-oxo-10-(3-cyclopentylpropionamido)-4H-pyrimido[1,2-C]quinazoline-3-carboxylate | HCID 13060558 | 70.5% |
반응 단계
A mixture of dimethyl [[6-(3-cyclopentylpropionamido)-4-quinazolinylamino]methylene]propanedioate (6.9 g) in diphenyl ether (53 ml) was stirred at 255° C. for 15 minutes and cooled to ambient temperature. The resulting solid was collected, washed with hexane and dried. There was obtained methyl 4-oxo-10-(3-cyclopentylpropionamido)-4H-pyrimido[1,2-C]quinazoline-3-carboxylate (4.5 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04377580 |
|---|
| 출처 데이터셋 | uspto-grants-1983_03 |
|---|
| ORD ID | ord-f077d5dee8074588b39bb6bb6c8adc6a |
|---|
| 출처 메모 | uspto-grants-1983_03 |
|---|
