참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | Ethyl 4-hydroxypiperidine-1-carboxylate | HCID 96394 | — |
| 반응물 | Bromodiphenylmethane | HCID 236603 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | Ethyl 4-(diphenylmethoxy)piperidine carboxylate | HCID 10020094 | — |
반응 단계
A mixture of 17.3 parts of 1-(ethoxycarbonyl)-4-hydroxypiperidine, 24.7 parts of bromodiphenylmethane and 7 parts of potassium carbonate is stirred and heated in an oil-bath for 3 hours at 140° C. The reaction mixture is cooled, water is added and the product is extracted with methylbenzene. The extract is washed a few times with water, dried, filtered and evaporated. The oily residue is distilled, yielding ethyl 4-(diphenylmethoxy)-1-piperidinecarboxylate; bp. 150° C. at 0.4 mm. pressure.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04377578 |
|---|
| 출처 데이터셋 | uspto-grants-1983_03 |
|---|
| ORD ID | ord-276822bab8634971bcbaf70aa53751a4 |
|---|
| 출처 메모 | uspto-grants-1983_03 |
|---|
