참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | 3,4-Dimethylpyridine | HCID 11417 | — |
| 반응물 | Selenium Dioxide | HCID 24007 | — |
| 용매 | Diphenyl Ether | HCID 7583 | — |
| 생성물 | 3-Methyl-isonicotinic acid | HCID 1502003 | 44% |
반응 단계
To a hot (155° C.) solution of 10.7 g (0.1 mol) of 3,4-lutidine in 100 mL diphenylether, was added 18 g (0.16 mol) selenium dioxide in portions. After about 20 minutes, the reaction was heated to 185° C. and allowed to react for approximately thirty minutes. After cooling, the reaction mixture was diluted with water and filtered. The filtrate was extracted with chloroform and the chloroform extracts were then concentrated under reduced pressure to provide 6.0 g of a pale brown solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US05837710 |
|---|
| 출처 데이터셋 | uspto-grants-1998_11 |
|---|
| ORD ID | ord-5e97c1971bd84e7ea84fdec6e05b09fe |
|---|
| 출처 메모 | uspto-grants-1998_11 |
|---|
