Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Pyridine → 3-(Bromomethyl)benzoic acid, 3-(hexadecyloxy)-2-methoxypropyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Pyridine | HCID 1049 | — |
| 반응물 | 1-O-hexadecyl-2-O-methylglycerol | HCID 1380 | — |
| 반응물 | 3-(Bromomethyl)benzoyl chloride | HCID 14471076 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 3-(Bromomethyl)benzoic acid, 3-(hexadecyloxy)-2-methoxypropyl ester | HCID 57087588 | 78.3% |
반응 단계
a mixture of 8 g of 3-(hexadecyloxy)-2-methoxypropanol, 6.22 g of m-bromomethylbenzoyl chloride, 2.11 g of pyridine and 80 ml of tetrahydrofuran was stirred for 48 hours, then filtered and evaporated. The residue was purified by chromatography and crystallized giving 10 g of 3-(bromomethyl)benzoic acid, 3-(hexadecyloxy)-2-methoxypropyl ester as white solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05411983 |
| 출처 데이터셋 | uspto-grants-1995_05 |
| ORD ID | ord-e5e0c058700b43d692f14a2aadf27ffa |
| 출처 메모 | uspto-grants-1995_05 |