참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 2-(Ethylamino)ethanol | HCID 8072 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 4-Fluorobenzaldehyde | HCID 68023 | — |
| 용매 | Dimethyl Sulfoxide | HCID 679 | — |
| 생성물 | 4-(Ethyl(2-hydroxyethyl)amino)benzaldehyde | HCID 639857 | — |
반응 단계
To a three neck flask fitted with a mechanical stirrer, a thermometer, and a condenser, is added 124 g (1 mole) of 4-fluorobenzaldehyde, 89.1 g (1 mole) of 2-(N-ethylamino)ethanol, 138.2 g (1 mole) of anhydrous potassium carbonate, and dimethylsulfoxide. The mixture is heated at 95° C. for 3 hours. After cooling to room temperature, the solution is poured into a four-fold excess of ice water, and the solid product is collected by filtration and recrystallized from water.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US05002361 |
|---|
| 출처 데이터셋 | uspto-grants-1991_03 |
|---|
| ORD ID | ord-6fe9943297e849958902c69afb4699f7 |
|---|
| 출처 메모 | uspto-grants-1991_03 |
|---|
