Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methylparaben → HCID 67689272, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methylparaben | HCID 7456 | — |
| 반응물 | Cephalexin | HCID 27447 | — |
| 반응물 | Cephalexin Monohydrate | HCID 62921 | — |
| 반응물 | Potassium Fluoride | HCID 522689 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | HCID 67689272 | HCID 67689272 | — |
반응 단계
Methyl paraben (375 mg, 2.5 mmol) in 150 ml of water was added to cephalexin monohydrate (2.4 g, 6.6 mmol) to result in a suspension. After 5 days at 5° C., the crystals were collected by filtration and washed with water to give 1.06 g (2.0 mmol) of cocrystals. mp 168°-169° C. Anal. calcd for C24H25N3O7S·H2O: C, 55.70; H, 5.26; N, 8.12. Found: C, 55.65; H, 5.28; N, 8.13. HPLC assay (calcd), found: (67.1), 67.1% cephalexin, (29.4), 28.7% methyl paraben. KF (Calcd) , found: (3.5) , 4.0% water.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05412094 |
| 출처 데이터셋 | uspto-grants-1995_05 |
| ORD ID | ord-03cfd62b56564b7aaa9029b192fcff22 |
| 출처 메모 | uspto-grants-1995_05 |