Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3,4,5-Trimethoxybenzaldehyde → 2,4-Diamino-6-[(3,4,5-trimethoxyphenylmethyl)imino]quinazoline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3,4,5-Trimethoxybenzaldehyde | HCID 6858 | — |
| 반응물 | 2,4,6-Triamino-5-chloroquinazoline | HCID 152217 | — |
| 반응물 | HCID 178418361 | HCID 178418361 | — |
| 촉매 | Nickel | HCID 935 | — |
| 용매 | Glycol monoethyl ether | HCID 8076 | — |
| 생성물 | 2,4-Diamino-6-[(3,4,5-trimethoxyphenylmethyl)imino]quinazoline | HCID 67571147 | — |
반응 단계
In a similar manner, 2,4,6-triamino-5-chloroquinazoline can be reacted with 3,4,5-trimethoxybenzaldehyde and hydrogen in the presence of Raney nickel in 2-ethoxyethanol, affording the corresponding 2,4-diamino-6-[(3,4,5-trimethoxyphenylmethyl)imino]quinazoline. Step C of Example 15 describes in detail the preparation of this compound. In a similar manner there may also be prepared 2,4-diamino-6-(substituted-aminomethyl)quinazolines.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05874579 |
| 출처 데이터셋 | uspto-grants-1999_02 |
| ORD ID | ord-a6dc081829224a748c55a6838e327c10 |
| 출처 메모 | uspto-grants-1999_02 |