Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Tetrahydro-6-(phenylmethyl)-1H-pyrrolo(3,4-b)pyridine-5,7(2H,6H)-dione → 6-Benzyloctahydro-1H-pyrrolo[3,4-b]pyridine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Tetrahydro-6-(phenylmethyl)-1H-pyrrolo(3,4-b)pyridine-5,7(2H,6H)-dione | HCID 9899604 | — |
| 반응물 | Aluminium lithium hydride | HCID 21226445 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 6-Benzyloctahydro-1H-pyrrolo[3,4-b]pyridine | HCID 11356376 | — |
반응 단계
44 g (about 0.18 mol) of crude or pure 6-benzyl-5,7-dioxo-octahydropyrrolo[3,4-b ]pyridine are reduced with 15.2 g (0.40 mol ) of lithium aluminum hydride in 390 ml of absolute tetrahydrofuran in the course of 10 hours in accordance with the working instructions of Example Ic. 4.4 g of a colorless oil having a boiling point of 93°-95° C./0.06 mbar are obtained on distillation.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05416096 |
| 출처 데이터셋 | uspto-grants-1995_05 |
| ORD ID | ord-aa13b123f5d14aa8b7cc0c768242178d |
| 출처 메모 | uspto-grants-1995_05 |