Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → Isonicotinamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | 4-Cyanopyridine | HCID 7506 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | Isonicotinamide | HCID 15074 | 91.4% |
반응 단계
(0.0051 g, 0.0119 mmol) of the platinum complex, prepared as in Example 1, was stirred with 4-cyanopyridine (2.0 g, 0.019 mol) and 0.75 ml (0.042 mol) of water and 10 ml tetrahydrofuran and the mixture heated under reflux for 4 hours. After cooling the liquids were removed using a rotary evaporator to give pyridine 4-carboxamide (2.12 g) corresponding to 90% yield.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06133478 |
| 출처 데이터셋 | uspto-grants-2000_10 |
| ORD ID | ord-abe4130096944c17b8c663f5db1a3233 |
| 출처 메모 | uspto-grants-2000_10 |