Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methanol → 3-(3-Pyrazolyl) propylguanidine hemisulphate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methanol | HCID 887 | — |
| 반응물 | S-methyl isothiourea hemisulfate | HCID 6604939 | — |
| 반응물 | 3-(1H-Pyrazol-3-yl)propan-1-amine | HCID 178510927 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 3-(3-Pyrazolyl) propylguanidine hemisulphate | HCID 178512790 | — |
반응 단계
An intimate mixture of 3-(3-aminopropyl)pyrazole (4.7 g) and S-methylthiouronium sulphate (4.9 g) is fused at 140° C for one hour. After cooling, methanol is added and the filtered methanol solution is subsequently diluted with ethanol. The solid obtained is recrystallised from methanol-ethanol affording 3-(3-pyrazolyl) propylguanidine hemisulphate, m.p. 210° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04088769 |
| 출처 데이터셋 | uspto-grants-1978_05 |
| ORD ID | ord-210157ad84694e7fa3c641721d66171b |
| 출처 메모 | uspto-grants-1978_05 |