Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Trifluoromethylcinnamic acid → 1H-Purine-2,6-dione, 3,7-dihydro-1,3-diethyl-8-(2-(3-(trifluoromethyl)phenyl)ethenyl)-, (E)-
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Trifluoromethylcinnamic acid | HCID 85527 | — |
| 반응물 | 5,6-Diamino-1,3-diethyluracil | HCID 4572133 | — |
| 생성물 | 1H-Purine-2,6-dione, 3,7-dihydro-1,3-diethyl-8-(2-(3-(trifluoromethyl)phenyl)ethenyl)-, (E)- | HCID 6448932 | — |
반응 단계
Substantially the same procedure as in Example 7 was repeated using 2.50 g (12.6 mmol) of 5,6-diamino-1,3-diethyluracil and 3.0 g (13.9 mmol) of 3-trifluoromethylcinnamic acid. Then, the resultant crude crystals were recrystallized from acetonitrile/water to give 2.07 g (yield of Compound 156 as white needles.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05484920 |
| 출처 데이터셋 | uspto-grants-1996_01 |
| ORD ID | ord-971079775d22481d97bdcfe29fbfb2d6 |
| 출처 메모 | uspto-grants-1996_01 |