Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethyl N-methylaminoacetate hydrochloride → N-Methyl-N-[2-(2,4,6-trimethylphenyl)-2-cyanovinyl]-glycine ethyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethyl N-methylaminoacetate hydrochloride | HCID 171173 | — |
| 반응물 | 3-Oxo-2-(2,4,6-trimethyl-phenyl)-propionitrile | HCID 22474397 | — |
| 용매 | Benzene | HCID 241 | — |
| 생성물 | N-Methyl-N-[2-(2,4,6-trimethylphenyl)-2-cyanovinyl]-glycine ethyl ester | HCID 54495113 | — |
반응 단계
A mixture of a-formyl-2,4,6 trimethylphenylacetonitrile (4.5 g, 24 mmol) and sarcosine ethyl ester hydrochloride (3.7 g, 24 mmol) in 100 mL of benzene was refluxed in a Dean-Stark apparatus for 16 h. The solvent was removed in vacuo to afford N-Methyl-N-[2-(2,4,6-trimethylphenyl)-2-cyanovinyl]-glycine ethyl ester as a pale yellow oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06020492 |
| 출처 데이터셋 | uspto-grants-2000_02 |
| ORD ID | ord-9f07f7596cc6487eb7a338c6a776959a |
| 출처 메모 | uspto-grants-2000_02 |