Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl iodide → 1,2,2,6,6-Pentamethyl-4-piperidone hydroiodide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl iodide | HCID 6328 | — |
| 반응물 | 4-Piperidinone, 2,2,6,6-tetramethyl-, monohydrate | HCID 22397602 | — |
| 용매 | Isopropanol | HCID 3776 | — |
| 생성물 | 1,2,2,6,6-Pentamethyl-4-piperidone hydroiodide | HCID 22397573 | 46% |
반응 단계
A solution of 2,2,6,6-tetramethyl-4-piperidone monohydrate (40 g, 23.1 mmol) and methyl iodide (98.31 g, 69.3 mmol) in isopropyl alcohol (25 mL) was stirred at RT for 48 h. The resulting suspension was filtered, the solid residue was dried and recrystallized from MeOH. After filtration and repeated washings with MeOH the solid was dried giving pure title compound (31.6 g, 10.6 mmol, yield 46.0%) as pale brown crystals.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06025390 |
| 출처 데이터셋 | uspto-grants-2000_02 |
| ORD ID | ord-eae7e283f1c043a3a0d4c9e0ca3c482b |
| 출처 메모 | uspto-grants-2000_02 |