Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetic Acid → Methyl 5-(2,4-dioxothiazolidin-5-ylidene)methyl-2-methoxybenzoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetic Acid | HCID 176 | — |
| 반응물 | Thiazolidinedione | HCID 5437 | — |
| 반응물 | Ammonium Acetate | HCID 517165 | — |
| 반응물 | Methyl 5-formyl-2-methoxybenzoate | HCID 10856352 | — |
| 용매 | Benzene | HCID 241 | — |
| 생성물 | Methyl 5-(2,4-dioxothiazolidin-5-ylidene)methyl-2-methoxybenzoate | HCID 54363563 | 86% |
반응 단계
A mixture of methyl 5-formyl-2-methoxybenzoate (490 mg), thiazolidine-2,4-dione (358 mg), ammonium acetate (401 mg), acetic acid (0.8 ml) and benzene (10 ml) was submitted to Dean-Stalk dewatering apparatus to reflux for 4 hours under heat. After cooling, the crystals deposited were collected by filtration, washed with benzene and with 20% aqueous solution of acetone, and then dried to obtain 634 mg (86%) of aimed compound as crystals.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06030990 |
| 출처 데이터셋 | uspto-grants-2000_02 |
| ORD ID | ord-03287fb8b777420db9a2b3b5043438ca |
| 출처 메모 | uspto-grants-2000_02 |