Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dimethylformamide → 8-(4-Benzyloxy-phenyl)-7-oxo-7H-thieno[2,3-a]quinolizine-10-carboxylic acid isopropyl-(2-methoxy-ethyl)-amide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dimethylformamide | HCID 6228 | — |
| 반응물 | Thionyl Chloride | HCID 24386 | — |
| 반응물 | N-(2-Methoxyethyl)isopropylamine | HCID 551575 | — |
| 반응물 | 8-[p-(benzyloxy)phenyl]-7-oxo-7H-thieno[2,3-a]quinolizine-10-carboxylic acid | HCID 19353629 | — |
| 용매 | Toluene | HCID 1140 | — |
| 용매 | Triethylamine | HCID 8471 | — |
| 용매 | 1,4-Dioxane | HCID 31275 | — |
| 생성물 | 8-(4-Benzyloxy-phenyl)-7-oxo-7H-thieno[2,3-a]quinolizine-10-carboxylic acid isopropyl-(2-methoxy-ethyl)-amide | HCID 56629768 | — |
반응 단계
From 8-[p-(benzyloxy)phenyl]-7-oxo-7H-thieno[2,3-a]quinolizine-10-carboxylic acid with SOCl2 and DMF in toluene. Then treatment with triethylamine and isopropyl-(2-methoxy-ethyl)-amine in dioxan.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06030984 |
| 출처 데이터셋 | uspto-grants-2000_02 |
| ORD ID | ord-11e1f58d569448248917e951548596ef |
| 출처 메모 | uspto-grants-2000_02 |