Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Trifluoroacetic acid → 5-(4-Bromophenyl)-1H-1,2,4-triazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Trifluoroacetic acid | HCID 6422 | — |
| 반응물 | HCID 68670520 | HCID 68670520 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 5-(4-Bromophenyl)-1H-1,2,4-triazole | HCID 46948734 | — |
반응 단계
Into a 2000 mL 3-necked flask was placed a solution of tert-butyl 3-(4-bromophenyl)-4H-1,2,4-triazole-4-carboxylate (80.0 g, 247 mmol) in CH2Cl2 (800 mL). To the mixture was added TFA (400 mL). The resulting solution was stirred at room temperature for 1 h. The reaction was evaporated to provide 3-(4-bromophenyl)-1H-1,2,4-triazole as a white solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08367706B2 |
| 출처 데이터셋 | uspto-grants-2013_02 |
| ORD ID | ord-dcd341de968f441c99e32ed2b998a0b9 |
| 출처 메모 | uspto-grants-2013_02 |