Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-(2,3-Xylyl)piperazine → 1-(2,3-dimethylphenyl)-4-(3-(1-phenyl-3-propyl-1H-pyrazol-5-yl)propyl)piperazine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-(2,3-Xylyl)piperazine | HCID 70541 | — |
| 반응물 | Diisopropylethylamine | HCID 81531 | — |
| 반응물 | Sodium triacetoxyborohydride | HCID 5049666 | — |
| 반응물 | HCID 86639932 | HCID 86639932 | — |
| 생성물 | 1-(2,3-dimethylphenyl)-4-(3-(1-phenyl-3-propyl-1H-pyrazol-5-yl)propyl)piperazine | HCID 68554245 | — |
반응 단계
146 mg (78%) of target compound was obtained by using a method same as in Example 1 by using 3-(1-phenyl-3-propyl-1H-pyrazol-5-yl)propanal (100 mg, 0.413 mmol), 1-(2,3-dimethylphenyl)piperazine (79 mg, 0.413 mmol), DIPEA (0.110 mL, 0.620 mmol) and NaBH(OAc)3 (263 mg, 1.239 mmol).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08372844B2 |
| 출처 데이터셋 | uspto-grants-2013_02 |
| ORD ID | ord-7c739a4b97d84f3bba2f051cfcfd6502 |
| 출처 메모 | uspto-grants-2013_02 |