Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sulfuric acid magnesium salt (1:1) → HCID 86633726, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sulfuric acid magnesium salt (1:1) | HCID 24083 | — |
| 반응물 | Tert-butyl 4-{[(2-chloro-3-nitroquinolin-4-yl)amino]methyl}benzylcarbamate | HCID 86633725 | — |
| 생성물 | HCID 86633726 | HCID 86633726 | 96.9% |
반응 단계
The method of Part B of Example 1 was used to hydrogenate tert-butyl 4-{[(2-chloro-3-nitroquinolin-4-yl)amino]methyl}benzylcarbamate (20 g, 45 mmol) with the modification that magnesium sulfate was added to the mixture before filtration. tert-Butyl 4-{[(3-amino-2-chloroquinolin-4-yl)amino]methyl}benzylcarbamate (18 g) was isolated as a thick, orange-red oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08377957B2 |
| 출처 데이터셋 | uspto-grants-2013_02 |
| ORD ID | ord-543346b76bb447bab8458f6adcd52999 |
| 출처 메모 | uspto-grants-2013_02 |