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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 3891생성일: 2026년 10월 24일

N-(((1-(2-Naphthalenylmethyl)-4-piperidinyl)amino)carbonyl)benzamide → [1-(Naphth-2-ylmethyl)piperid-4-yl]urea

https://huagongshe.com/ko/reaction/3891

반응식

참여 물질

역할이름HCID투입량
반응물N-(((1-(2-Naphthalenylmethyl)-4-piperidinyl)amino)carbonyl)benzamideHCID 72002—
용매Sodium HydroxideHCID 14798—
생성물[1-(Naphth-2-ylmethyl)piperid-4-yl]ureaHCID 13145794—

반응 단계

1-Benzoyl-3-[1-(naphth-2-ylmethyl)piperid-4-yl]urea (prepared acccording to Example 1) is hydrolysed by refluxing in 2N sodium hydroxide to give [1-(naphth-2-ylmethyl)piperid-4-yl]urea(m.p. 183°-5° C.). The product is acylated by reaction with 4-methoxybenzoyl chloride to give the title compound, m.p. of HCL, quarterhydrate=193°-193.5° C.).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US04722930
출처 데이터셋uspto-grants-1988_02
ORD IDord-f835042249204abe88c806390379a6a4
출처 메모uspto-grants-1988_02