Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
CID 367964 → 3-(4-Fluorophenyl)-2-methylpropanoic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | CID 367964 | HCID 367964 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 3-(4-Fluorophenyl)-2-methylpropanoic acid | HCID 15487791 | — |
반응 단계
To p-fluoro-α-methylcinnamic acid (177.9 g, 0.987 mol) in 3.6 l ethanol is added 11.0 g of 5% Pd/C. The mixture is reduced at room temperature under a hydrogen pressure of 40 p.s.i. When hydrogen uptake ceases, the catalyst is filtered off, and the solvent is evaporated in vacuo to give the product, p-fluoro-α-methylhydrocinnamic acid, which was used directly in the next step.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06610854B2 |
| 출처 데이터셋 | uspto-grants-2003_08 |
| ORD ID | ord-2dc4991087f549b8b09d7683aeec0ff9 |
| 출처 메모 | uspto-grants-2003_08 |