Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Pentafluorobenzoyl chloride → 5-(N-[2,3,4,5,6-pentafluorobenzoyl]amino)-3-(1-methylpiperidin-4-yl)pyrrolo[3,2-b]pyridine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Pentafluorobenzoyl chloride | HCID 75256 | — |
| 반응물 | 3-(1-Methyl-piperidin-4-yl)-1H-pyrrolo[3,2-b]pyridin-5-ylamine | HCID 10220230 | — |
| 생성물 | 5-(N-[2,3,4,5,6-pentafluorobenzoyl]amino)-3-(1-methylpiperidin-4-yl)pyrrolo[3,2-b]pyridine | HCID 19601485 | 85.7% |
반응 단계
Beginning with 0.010 gm (0.044 mMol) 5-amino-3-(1-methylpiperidin-4-yl)pyrrolo[3,2-b]pyridine and 0.008 mL (0.053 mMol) 2,3,4,5,6-pentafluorobenzoyl chloride, 0.016 gm (84%) of the title compound were prepared essentially by the procedure described in Example 7.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05817671 |
| 출처 데이터셋 | uspto-grants-1998_10 |
| ORD ID | ord-805ac523b2b84360be3889c01517b319 |
| 출처 메모 | uspto-grants-1998_10 |