Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl Bromide → 2-Bromo-6-ethoxynaphthalene
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl Bromide | HCID 6323 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 6-Bromo-2-naphthalenol | HCID 27144 | — |
| 용매 | Acetone | HCID 180 | — |
| 생성물 | 2-Bromo-6-ethoxynaphthalene | HCID 236858 | — |
반응 단계
This experimental procedure is an O-alkylation. A solution of bromomethane (48.90 g, 0.45 mol) is added dropwise to a stirred refluxing mixture of 6-Bromo-2-naphthol (40.00 g, 0.18 mol) and potassium carbonate (63.00 g, 0.46 mol) in acetone. The stirred mixture is heated under reflux for 24 hours (ie until glc analysis reveals a complete reaction). The potassium carbonate is filtered off, water is added to filtrate and the product is recrystallised from ethanol to give a yield of 43.92 g (97%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05820781 |
| 출처 데이터셋 | uspto-grants-1998_10 |
| ORD ID | ord-a2e80eb80d1047d1a23f28aea9355410 |
| 출처 메모 | uspto-grants-1998_10 |