Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Chloroquinazolin-6-yl acetate → 6-Acetoxy-4-[3-methyl-4-(2-pyridylmethoxy)anilino]quinazoline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Chloroquinazolin-6-yl acetate | HCID 18967624 | — |
| 반응물 | 3-Methyl-4-(pyridin-2-ylmethoxy)aniline | HCID 23438288 | — |
| 생성물 | 6-Acetoxy-4-[3-methyl-4-(2-pyridylmethoxy)anilino]quinazoline | HCID 18967611 | 35% |
반응 단계
Using an analogous procedure to that described in Example 1, 6-acetoxy-4-chloroquinazoline was reacted with 5-amino-2-tolyl 2-pyridylmethyl ether to give 6-acetoxy-4-[3-methyl-4-(2-pyridylmethoxy)anilino]quinazoline in 35% yield, m.p. 149°-151° C.;
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05821246 |
| 출처 데이터셋 | uspto-grants-1998_10 |
| ORD ID | ord-2da5c69a5636427698c7bb8d64aa4f81 |
| 출처 메모 | uspto-grants-1998_10 |