Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-(1,3-Dimethylbutyl)aniline → HCID 16727057, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-(1,3-Dimethylbutyl)aniline | HCID 11528441 | — |
| 반응물 | HCID 178418361 | HCID 178418361 | — |
| 촉매 | Ruthenium | HCID 23950 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | HCID 16727057 | HCID 16727057 | — |
반응 단계
5 g of Ru/C (5%) are added to a solution comprising 20.0 g (0.113 mol) of 2-(1,3-dimethylbutyl)aniline in 300 ml of tetrahydrofuran, and the mixture is hydrogenated with 100 bar of hydrogen at 120° C. for 24 hours. After cooling to room temperature, the catalyst is filtered off through Celite 545 and the product is concentrated under reduced pressure. This gives 19.1 g (92.4% of theory) of 2-(1,3-dimethylbutyl)cyclohexanamine having a purity of 100% according to HPLC and a log P (pH 2.3) of 4.07.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08748471B2 |
| 출처 데이터셋 | uspto-grants-2014_06 |
| ORD ID | ord-55aacbb9f58a402fb88f90826dbc2b0e |
| 출처 메모 | uspto-grants-2014_06 |