Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
D-Lactic Acid → HCID 67334983, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | D-Lactic Acid | HCID 61503 | — |
| 반응물 | Diisopropylethylamine | HCID 81531 | — |
| 반응물 | (3R)-(+)-3-(tert-Butoxycarbonylamino)pyrrolidine | HCID 1514397 | — |
| 반응물 | Methanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1) | HCID 2733084 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | HCID 67334983 | HCID 67334983 | 96.9% |
반응 단계
[(R)-1-((R)-2-Hydroxy-propionyl)-pyrrolidin-3-yl]carbamic acid tert-butyl ester (500 mg) was prepared by following General Procedure F starting from (R)-2-hydroxy-propionic acid (200 mg), (R)-pyrrolidin-3-yl-carbamic acid tert-butyl ester (372 mg), HBTU (800 mg), and DIEA (400 uL) in DMF (4 mL).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08759535B2 |
| 출처 데이터셋 | uspto-grants-2014_06 |
| ORD ID | ord-ab4eaada386d4637854c0e70de4c8953 |
| 출처 메모 | uspto-grants-2014_06 |