참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Benzyl Bromide | HCID 7498 | — |
| 반응물 | Ethyl Acetate | HCID 8857 | — |
| 반응물 | Lithium Carbonate | HCID 11125 | — |
| 반응물 | 2,5-Dihydroxybenzaldehyde | HCID 70949 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | 2-(Benzyloxy)-5-hydroxybenzaldehyde | HCID 18536192 | — |
반응 단계
To a solution of 2,5-dihydroxybenzaldehyde (10.41 g, 75.4 mmol) in 100 mL of DMF was added lithium carbonate (16.71 g, 226 mmol), followed by benzyl bromide (13.5 mL, 113 mmol). The solution was warmed to 60° C. and stirred for 30 hours. The reaction was poured into EtOAc and washed with water, saturated NaHCO3 solution and brine, dried (Na2SO4), filtered, and concentrated in vacuo. The product was isolated as a brown oil which was used without further purification.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US06562823B1 |
|---|
| 출처 데이터셋 | uspto-grants-2003_05 |
|---|
| ORD ID | ord-3644a0c03a8047b489215c373b988329 |
|---|
| 출처 메모 | uspto-grants-2003_05 |
|---|
