Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Bromobenzene → 1-Phenylnaphthalene
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Bromobenzene | HCID 7961 | — |
| 반응물 | 1-Naphthaleneboronic acid | HCID 254532 | — |
| 반응물 | Potassium Fluoride | HCID 522689 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 1-Phenylnaphthalene | HCID 11795 | 99.8% |
반응 단계
Bromobenzene (82 mg, 0.52 mmol) reacted with 1-naphtylboronic acid (110 mg, 0.64 mmol) using 1 mol % of Pd(dba)2/Ph5FcP(t-Bu)2 and KF (90 mg, 1.55 mmol) in THF (2 ml) at room temperature to give the title compound (106 mg, 99%) as a colorless oil: 1H-NMR (400 MHz, CDCl3): δ 7.99-7.91 (m, 3H), 7.60-7.47 (m, 9H). 13C{1H}-NMR (100 MHz, CDCl3): δ 140.71, 140.21, 133.75, 131.57, 130.05, 128.23, 127.60, 127.21, 126.90, 125.99, 125.74, 125.36. GC/MS(EI): m/z 204 (M+). Anal. Calcd for C16H12: C, 94.08; H, 5.92. Found: C, 93.96; H, 6.11.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06562989B2 |
| 출처 데이터셋 | uspto-grants-2003_05 |
| ORD ID | ord-0f80ff7842a64c5bb279eb12fa5d5350 |
| 출처 메모 | uspto-grants-2003_05 |