참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 1-Decanol | HCID 8174 | — |
| 반응물 | 3-Bromothiophene | HCID 13383 | — |
| 반응물 | Sodium | HCID 5360545 | — |
| 촉매 | Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI) | HCID 24350 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 3-Decyloxythiophene | HCID 19760690 | — |
반응 단계
3-Decyloxythiophene was synthesized as follows. 1-Decanol (0.51 mol, 80.27 g) was added dropwise to 3.5 g (0.15 mol) of sodium metal. After complete disappearance of sodium, the residual alcohol was removed in vacuum and the remaining solid was dissolved in 20˜30 ml DMF. After the solution was heated to 110° C., 12.2 g (0.075 mol) of 3-bromo-thiophene and 1.0 g (0.00053 mol) of copper (I) iodide were added. After 16 hrs of stirring at 110° C., the mixture was poured into water and extracted with ether three times. The filtrate was concentrated in vacuo and the yellow oily residue was chromatographed on a silica column using hexane as the eluent to yield 15.5 g of yellow liquid (86% yield). Mw=240.4. Element Anal. Calcd for C14H24SO: C, 69.94; H, 10.06; 0, 6.66; S, 13.34. Found: C, 69.90; H, 10.00; 0, 6.64; S, 13.30.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US08530594B2 |
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| 출처 데이터셋 | uspto-grants-2013_09 |
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| ORD ID | ord-4e17e7d239a34bc080fa141765d91d78 |
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| 출처 메모 | uspto-grants-2013_09 |
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