Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-[2-(5-Fluoro-2-methoxyphenyl)-2-methylpropyl]-2-trifluoromethyloxirane → Ethyl 3-(4-{[4-[5-fluoro-2-(methyloxy)phenyl]-2-hydroxy-4-methyl-2-(trifluoro methyl)pentyl]amino}-1h-indazol-1-yl)benzoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-[2-(5-Fluoro-2-methoxyphenyl)-2-methylpropyl]-2-trifluoromethyloxirane | HCID 16099239 | — |
| 반응물 | Ethyl 3-(4-amino-1H-indazol-1-yl)benzoate | HCID 57615935 | — |
| 생성물 | Ethyl 3-(4-{[4-[5-fluoro-2-(methyloxy)phenyl]-2-hydroxy-4-methyl-2-(trifluoro methyl)pentyl]amino}-1h-indazol-1-yl)benzoate | HCID 57615933 | — |
반응 단계
Prepared similarly to Example 1 from racemic 2-{2-[5-fluoro-2-(methyloxy)phenyl]-2-methylpropyl}-2-(trifluoromethyl)oxirane and ethyl 3-(4-amino-1H-indazol-1-yl)benzoate (Intermediate 6).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08093281B2 |
| 출처 데이터셋 | uspto-grants-2012_01 |
| ORD ID | ord-2db637197d0147de81398715378b8c9d |
| 출처 메모 | uspto-grants-2012_01 |