Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-(3-Bromopropoxy)tetrahydro-2H-pyran → 5-(2-Methylsulfanylpyrimidin-4-yl)-2-[3-(tetrahydropyran-2-yloxy)propyl]-6-(3-trifluoromethylphenyl)pyrazolo[3,4-b]pyridine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-(3-Bromopropoxy)tetrahydro-2H-pyran | HCID 2777988 | — |
| 반응물 | 5-[2-(methylsulfanyl)pyrimidin-4-yl]-6-[3-(trifluoromethyl)phenyl]-1H-pyrazolo[3,4-b]pyridine | HCID 67013869 | — |
| 생성물 | 5-(2-Methylsulfanylpyrimidin-4-yl)-2-[3-(tetrahydropyran-2-yloxy)propyl]-6-(3-trifluoromethylphenyl)pyrazolo[3,4-b]pyridine | HCID 67014547 | — |
반응 단계
Following a similar procedure to that described in examples 6 and 7, but starting from 5-[2-(methylsulfanyl)pyrimidin-4-yl]-6-[3-(trifluoromethyl)phenyl]-1H-pyrazolo[3,4-b]pyridine (obtained in example 126) and 2-(3-bromopropoxy)tetrahydropyran, the title compound was obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08536194B2 |
| 출처 데이터셋 | uspto-grants-2013_09 |
| ORD ID | ord-57193f1841a74ffb8d4227914efa1b74 |
| 출처 메모 | uspto-grants-2013_09 |