Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Nitrogen → 1-(2-Bromo-1,3-thiazol-5-yl)ethan-1-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Nitrogen | HCID 947 | — |
| 반응물 | 1-(2-Bromothiazol-5-yl)ethanol | HCID 59135194 | — |
| 촉매 | Manganese dioxide | HCID 14801 | — |
| 용매 | 2-Oxopropiononitrile | HCID 69430 | — |
| 생성물 | 1-(2-Bromo-1,3-thiazol-5-yl)ethan-1-one | HCID 57562813 | — |
반응 단계
In a flame dried round-bottomed flask equipped with a magnetic stir bar and under inert atmosphere (N2), a solution of 1-(2-bromo-thiazol-5-yl)-ethanol (1.95 g, 9.37 mmol) in AcCN (90.0 mL) was treated at rt with MnO2 (4.53 g, 46.86 mmol) and the reaction mixture was stirred for 16 h at rt before being filtered through Celite. The solvent was removed under reduced pressure to give the title compound as a yellow solid. LC-MS-conditions 02: tR=0.80 min.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08536209B2 |
| 출처 데이터셋 | uspto-grants-2013_09 |
| ORD ID | ord-094e635c55654d0c904bdd36fffc728b |
| 출처 메모 | uspto-grants-2013_09 |