Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-(2-Morpholinoethoxy)benzaldehyde → 3-Hydroxy-3-[4-[2-(4-morpholinyl)-ethoxy]-phenyl]-1-propyne
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-(2-Morpholinoethoxy)benzaldehyde | HCID 3719902 | — |
| 반응물 | HCID 178462451 | HCID 178462451 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 3-Hydroxy-3-[4-[2-(4-morpholinyl)-ethoxy]-phenyl]-1-propyne | HCID 18359221 | — |
반응 단계
3-Hydroxy-3-[4-[2-(4-morpholinyl)-ethoxy]-phenyl]-1-propyne was prepared according to Method A above from 4-[2-(4-morpholinyl)-ethoxy]-benzaldehyde (0.630 g, 2.68 mmol) (see below) in THF (20 mL) and ethynylmagnesium chloride (3.0 mmol, 6 mL, 0.5M solution in tetrahydrofuran) (Aldrich). (Yield 492 mg, 70%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06313310B1 |
| 출처 데이터셋 | uspto-grants-2001_11 |
| ORD ID | ord-841638b967d8442f87b038aa1e22ece7 |
| 출처 메모 | uspto-grants-2001_11 |