Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → 3-Methyl-1,2-oxazole-4-carboxylic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | Ethyl 3-methyl-1,2-oxazole-4-carboxylate | HCID 317668 | — |
| 용매 | Ethanol | HCID 702 | — |
| 용매 | Sodium Hydroxide | HCID 14798 | — |
| 생성물 | 3-Methyl-1,2-oxazole-4-carboxylic acid | HCID 4589692 | 93.9% |
반응 단계
Ethyl 3-methyl-4-isoxazolecarboxylate (1.3 g) is stirred at room temperature overnight in 5 mL of ethanol and 10 mL of 2.5 N sodium hydroxide. Dilution with water, cooling in ice, and acidification to pH 2 with 6 N hydrochloric acid precipitates an off-white solid which is collected by vacuum filtration, washed with ethanol/water, and dried under vacuum to give 1.0 g of 3-methyl-4-isoxazolecarboxylic acid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06316479B1 |
| 출처 데이터셋 | uspto-grants-2001_11 |
| ORD ID | ord-9955587e1bda49679ef964de91558d80 |
| 출처 메모 | uspto-grants-2001_11 |