Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N-bromobutanimide → 2-Bromo-5-methoxybenzyl bromide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N-bromobutanimide | HCID 67184 | — |
| 반응물 | 1-Bromo-4-methoxy-2-methylbenzene | HCID 117915 | — |
| 촉매 | Azobisisobutyronitrile | HCID 6547 | — |
| 용매 | 1,1-Dichloroethane | HCID 6365 | — |
| 생성물 | 2-Bromo-5-methoxybenzyl bromide | HCID 3525951 | 64% |
반응 단계
To a solution of 2-bromo-5-methoxytoluene (50 g, 0.25 mol) in dichloroethane (375 ml), N-bromosuccinimide (48.8 g, 0.275 mol) and AIBN (1.36 g) were added and the reaction was refluxed for 4 h. The cooled solution was filtered and the solvent was evaporated to give a weight of 44.8 g crude 1-Bromo-2-bromomethyl-4-methoxy-benzene (64% yield).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06323345B1 |
| 출처 데이터셋 | uspto-grants-2001_11 |
| ORD ID | ord-07f7a5122f7f4d769565c3dbd6b6dab5 |
| 출처 메모 | uspto-grants-2001_11 |