Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Chloro-4-methoxybenzeneboronic acid → 8-(2-Chloro-5-methoxy-phenyl)-quinoxaline-5-carboxylic acid [3-(4-ethyl-piperazin-1-yl)-phenyl]-amide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Chloro-4-methoxybenzeneboronic acid | HCID 2773330 | — |
| 반응물 | 3-(4-Ethylpiperazin-1-yl)aniline | HCID 22330105 | — |
| 반응물 | 8-(2-Chloro-5-methoxy-phenyl)quinoxaline-5-carboxylic acid | HCID 66914608 | — |
| 생성물 | 8-(2-Chloro-5-methoxy-phenyl)-quinoxaline-5-carboxylic acid [3-(4-ethyl-piperazin-1-yl)-phenyl]-amide | HCID 44515980 | — |
반응 단계
The title compound was prepared in analogy to the procedure described in Step 14.1 but using 3-(4-ethyl-piperazin-1-yl)-aniline (Step 2.1) and 8-(2-chloro-5-methoxy-phenyl)quinoxaline-5-carboxylic acid. The latter compound was synthesized as described in Steps 1.2-1.7 but using 2-chloro-4-methoxyphenylboronic acid in Step 1.4. Title compound: ESI-MS: 502.1 [M]+; tR=3.57 min (System 3).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08536175B2 |
| 출처 데이터셋 | uspto-grants-2013_09 |
| ORD ID | ord-54b9a0c0860540bc82e8e387ee623d81 |
| 출처 메모 | uspto-grants-2013_09 |