Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Homoserine lactone hydrobromide → 3-(N'-(3,5-Difluorophenylacetyl)-L-alaninyl)-amino-gamma-butyrolactone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Homoserine lactone hydrobromide | HCID 73508 | — |
| 반응물 | (2S)-2-[[2-(3,5-difluorophenyl)acetyl]amino]propanoic acid | HCID 12135350 | — |
| 생성물 | 3-(N'-(3,5-Difluorophenylacetyl)-L-alaninyl)-amino-gamma-butyrolactone | HCID 86584967 | — |
반응 단계
Following General Procedure A above using N-(3,5-difluorophenylacetyl)-L-alanine (Example B) and α-amino-γ-butyrolactone hydrobromide (Aldrich), the title compound was prepared as a solid having a melting point of 174-177° C. The reaction was monitored by tlc on silica gel (Rf=0.52 in 10% methanol/dichloromethane) and purification was by silica gel chromatography.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06667305B1 |
| 출처 데이터셋 | uspto-grants-2003_12 |
| ORD ID | ord-f5d98214794b48d881acd85dcb2d2ed8 |
| 출처 메모 | uspto-grants-2003_12 |